Caninsulin Cartridges for VetPen - 2.7ml by 10 cartridges
This is a prescription medicine. A prescription is required from your veterinarian before we can supply this product. Please ensure that you have read the "How to Order" page before ordering this item.
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|Drug Name and Strength||An aqueous suspension of insulin containing 40 IU/mL of highly purified porcine insulin, 35% as amorphous zinc insulin and 65% as crystalline zinc insulin|
|Quantity||10 x 2.7ml cartidges|
|Indication||Diabetes mellitus in dogs and cats.|
|Contraindications||Do not use in food producing species of animals.|
|Actions||An insulin product with intermediate length of action. It contains porcine insulin, which is structurally identical to canine insulin. In cases of insulin deficiency and/or decreased insulin sensitivity, the required blood levels can be achieved by using an individually adjusted dose of Caninsulin VetPen insulin.|
|Precautions||It is important to establish a strict feeding schedule with a minimum of fluctuations and changes in consultation with the owner. Stress and irregular exercise must be avoided. Care must be taken with the use of corticosteroids. The use of progestogens (oestrus inhibitors) in animals with diabetes mellitus should be avoided. Ovariohysterectomy should be considered. Caninsulin VetPen insulin is not recommended for the initial treatment of animals presented with diabetic ketoacidosis. Hypoglycaemia is a potential sequel to insulin use. It is recommended that the owner is provided with strategies to prevent, recognise and respond to hypoglycaemia. Users with animals in transition from Caninsulin vials to Caninsulin VetPen should exercise care in ensuring correct product administration and following veterinary instructions.Disposal Dispose of empty container by wrapping with paper and putting in garbage.|
|Dosage and Administration||The Caninsulin VetPen cartridges are designed to be used with the Caninsulin VetPen 8 and VetPen 16 Veterinary Automatic Insulin Delivery Pens. Before loading cartridges into the pens, turn Caninsulin VetPen cartridges up and down at least 10 times until the insulin appears uniformly milky. Each VetPen cartridge contains two colourless glass beads to aid resuspension before use. Agglomerates can form in insulin suspension. Do not use the product if visible agglomerates persist after thorough mixing. The Caninsulin VetPen Insulin product may be provided with a VetPen Veterinary Automatic Delivery Pen. This device will have its own detailed instruction sheet for use in combination with the product. These instructions are to be strictly followed. Use all product within six weeks of withdrawing the first dose. Caninsulin VetPen insulin can be administered by subcutaneous injection. Alternate the injection site daily. The dose and frequency of administration depends on the degree of deficit in the animal's own insulin production and individual variations in metabolism leading to differences in the duration of activity. After an initial starting dose, the individual maintenance dose must be established by monitoring the animal's clinical response to insulin treatment, which usually includes interpretation of serial blood glucose curves and owner home monitoring records. The duration of activity of Caninsulin VetPen Insulin may be sufficient to achieve acceptable clinical control in some dogs with once daily administration. All other dogs will need to be treated with twice daily administration. The duration of action in cats is shorter than in dogs. All cats should be started on twice daily Caninsulin VetPen Insulin administration.Twice daily administration (cats and dogs). Starting doses. The starting dose is 0.25 to 0.5 IU/kg bodyweight twice daily, rounded down to the nearest whole unit (based on the animal's fasting blood glucose measurement prior to starting therapy). Blood glucose concentration < 20 mmol/L or < 3.6 g/L (< 360 mg/dL): give Caninsulin 0.25 IU/kg bodyweight twice daily. Blood glucose concentration ≥ 20 mmol/L or ≥ 3.6 g/L (≥ 360 mg/dL): give Caninsulin 0.5 IU/kg bodyweight twice daily. Obese cats and dogs: use ideal bodyweight to calculate the initial insulin dose. The daily food ration should be divided into two equal parts. Composition and quantity of the daily food intake should be constant. Administer the Caninsulin VetPen Insulin dose every 12 hours and feed half of the daily food ration with each injection. Dose adjustments, dogs. Subsequent adjustment to establish the maintenance dose should be made by increasing or decreasing the daily dose by approximately 10%, according to the evolution of the diabetes clinical signs, and according to the results of serial blood glucose measurements. Alterations in dose should not normally be made more frequently than every one to three weeks. Dose adjustments, cats. Subsequent adjustment to establish the maintenance dose should be made by increasing or decreasing the daily dose according to the evolution of the diabetes clinical signs, and according to results of serial blood glucose measurements. Alterations in dose should not normally be made more frequently than every one to three weeks. Increments of 1 IU per injection are recommended. Ideally no more than 2 IU per injection should be administered in the first three weeks of treatment. Due to the day to day variation in the blood glucose response, and the variations in insulin responsiveness that are seen with time, larger or more frequent increases in dose are not recommended.Once daily administration (dogs only). The initial daily dose is 0.5 IU/kg bodyweight once daily (rounded down to the nearest whole unit). The daily food ration should be divided into two equal parts. Composition and quantity of the daily food intake should be constant. Administer the Caninsulin dose with the first half of the daily ration and feed the second meal approximately 7.5 hours later (e.g. 08.30 and 16.00). Further dose adjustments should be made progressively as above for dogs.|
|Storage||Store unopened Caninsulin VetPen cartridges in an upright position between 2 and 8°C. (Refrigerate. Do not freeze. Protect from light.)|
|MSDS (external link)||Caninsulin|
|Label (external link)||Caninsulin VetPen|
|Manufacturer||MSD Animal Health|