Pentosan 100 20ml

Pentosan polysulfate sodium 100 mg/mL

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More Information
Drug Name and Strength Pentosan polysulfate sodium 100 mg/mL
Quantity 20ml Bottle
Indication Aid in the treatment of noninfectious joint diseases in dogs, including osteoarthritis, especially in conditions affecting multiple joints; osteochondrosis dissecans; traumatic joint and periarticular inflammation in working and racing dogs.
Contraindications Administration to dogs with clotting defects, traumatic haemorrhage, infection, renal or hepatic failure; administration within two days of surgery.
Actions Pharmacology Pentosan polysulfate is a semisynthetic polysaccharide polymer which possesses anti-inflammatory, antiarthritic and chondroprotective properties. These beneficial effects arise from direct anti-inflammatory activity; inhibition of neutrophil migration into joints; stimulation of hyaluronic acid synthesis by synovial fibroblasts which results in a marked increase in synovial fluid volume and viscosity; stimulation of chondrocytes and the biosynthesis of proteoglycans; and strong fibrinolytic activity which improves the circulation in subchondral bone and periarticular structures.
Precautions If using after surgery or trauma, ensure that all haemorrhage has ceased.
Dosage and Administration Give by subcutaneous or intramuscular injection. 3 mg/kg on four occasions with an interval of five to seven days between injections.
Storage Store below 30°C (room temperature). Do not freeze. Protect from light.
MSDS (external link) Pentosan 100 MSDS
Label (external link) Pentosan 100 Label
Manufacturer Ceva Animal Health Pty Limited
Refrigerated Product No
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