Prascend 1mg (160 tablets)
This is a prescription medicine. A prescription is required from your veterinarian before we can supply this product. Please ensure that you have read the "How to Order" page before ordering this item.
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|Indication||Control of clinical signs associated with pituitary pars intermedia dysfunction (equine Cushing disease) in horse and ponies.|
|Contraindications||Do not administer to horses with known hypersensitivity to pergolide mesylate or other ergot derivatives.|
|Precautions||Use with caution in breeding animals and pregnant or lactating mares. Safe use in these groups has not been established and the pharmacological action of pergolide mesylate suggests that it may interfere with reproductive functions such as lactation. Use with caution in horses less than 2 years of age.Harmful if swallowed. Wash hands after use.First Aid If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126.|
|Dosage and Administration||Administer orally once daily; can be given whole in a treat. To facilitate administration, the required daily dose can be placed in a small amount of water and/or mixed with molasses or other sweetener and agitated until dissolved. In this case, the dissolved tablets should be administered with a syringe and the whole amount should be administered immediately. Tablets should not be crushed.Starting dose. The average starting dose is pergolide 2 microgram/kg bodyweight; this should then be titrated according to the individual response as determined by monitoring.Starting dosage guide. 200 to 400 kg bodyweight. ½ a tablet (starting dose: 0.5 mg; dose range: 1.3 to 2.5 microgram/kg). 401 to 600 kg bodyweight. 1 tablet (starting dose: 1 mg; dose range: 1.7 to 2.5 microgram/kg). 601 to 850 kg bodyweight. 1½ tablets (starting dose: 1.5 mg; dose range: 1.8 to 2.5 microgram/kg). 851 to 1000 kg bodyweight. 2 tablets (starting dose: 2 mg; dose range: 2 to 2.4 microgram/kg).Maintenance dosage. Lifelong treatment is anticipated for this disease as clinical signs return if treatment is ceased. Most horses respond to therapy and are stabilised at an average dose of pergolide 2 microgram/kg bodyweight. Clinical improvement with pergolide is expected within six to 12 weeks but may vary depending on the severity of disease.|
|Storage||Store below 25°C (air conditioning).|
|Manufacturer||Boehringer Ingelheim Animal Health Australia Pty Ltd|