Zydax 100 20ml

sodium pentosan polysulfate(100mg/mL)

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More Information
Drug Name and Strength sodium pentosan polysulfate(100mg/mL)
Quantity 20ml Bottle
Indication An aid in the treatment of noninfectious inflammatory joint disease in dogs. Clinical applications include the following conditions: osteoarthritis, osteochondritis dissecans, traumatic joint and periarticular inflammation in working and racing dogs, and following intra-articular surgery.
Contraindications This product is contraindicated for use in dogs with congestive heart disease, severe renal disease, primary hepatic failure or oedema; and in bitches that are pregnant or lactating.
Actions Pentosan polysulfate sodium (PPS) is a semisynthetic polysaccharide with a linear xylan (pentosan) backbone. Xylan is a hemicellulose derived from plant origin. PPS possesses anti-inflammatory, antiarthritic and chondroprotective activities. The beneficial effects of pentosan polysulfate in joint disease are due to the following actions: anti-inflammatory activity; inhibition of neutrophil migration into the joint; stimulation of hyaluronic acid synthesis by synovial fibroblasts, resulting in increased volume and viscosity of synovial fluid; stimulation of proteoglycan synthesis by chondrocytes; and fibrinolytic activity, resulting in improved circulation to subchondral bone and periarticular structures.
Precautions First Aid If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126.Disposal Dispose of empty container by wrapping with paper and putting in garbage.
Dosage and Administration Dogs. Pentosan polysulfate sodium 3 mg/kg bodyweight (≡ 1 mL/33 kg) by subcutaneous or intramuscular injection on four occasions with an interval of five to seven days between injections.
Storage Store between 2 and 8°C. (Refrigerate. Do not freeze.) Protect from light. Following withdrawal of first dose, use the remainder of the vial within 28 days or discard the unused portion.
MSDS (external link) Zydax 100 MSDS
Label (external link) Zydax 100 Label
Manufacturer Parnell Australia Pty Ltd
Refrigerated Product Yes
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